Xanthomatous Hypophysitis: A Case Report and Literature Review

is clinically and radiologically important because it mimics tumor-like lesions in the sellar area and may produce mass effects. Xanthomatous hypophysitis is a type of primary hypophysitis with a very low prevalence. In previously reported cases (1-3), patients with xanthomatous hypophysitis sometimes presented with a headache, sexual dysfunction, and/or diabetes insipidus. A pituitary lesion with cystic change is evident by imaging as well as the diminishment of testosterone, FSH (follicle-stimulating hormone), and LH (luteinizing hormone) levels. The authors report a case of xanthomatous hypophysitis, which presented as an intrasellar cystic lesion, hypogonadism, and hyperprolactinemia. The report also includes a literature review. Case Report